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Your Position: Home > S-Glycoprotein B (HSV-2)

S-Glycoprotein B (HSV-2)

Brief Information

Name:Envelope glycoprotein B, gB
Target Synonym:UL55
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 2 Clinical

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Synonym Name

gB

Background

Epstein-Bar Virus (EBV), also known as human herpesvirus 4, belongs to gamma herpes virus family and is a very common human virus worldwide. EBV causes infectious mononucleosis (IM) and also associates to some specific types of cancers such as Burkitt’s lymphoma (BL) and gastric carcinoma (GC). Glycoprotein B (gB) plays an important role in viral entry by binding with αvβ6/αvβ8 integrins to trigger the membrane fusion and entry process of epithelial cells, which makes it become an great target for EBV research.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Fiztasovimab NPC-21 Phase 2 Clinical Nobelpharma Co Ltd Cytomegalovirus Infections Details
TRL-345 CMV-345; TRL-345 Phase 1 Clinical Trellis Bioscience LLC Cytomegalovirus Infections Details
Fiztasovimab NPC-21 Phase 2 Clinical Nobelpharma Co Ltd Cytomegalovirus Infections Details
TRL-345 CMV-345; TRL-345 Phase 1 Clinical Trellis Bioscience LLC Cytomegalovirus Infections Details

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